Biogenesis of Mitochondria

1. From pre existing mitochondria

Luck Claude and Tandler

A- By budding

• According to this theory – Double membranous bud are form from pre existing mitochondria
• which are develop and form new mitochondria

B- By septa formation

• In this method Mitochondria grow in length and form 2-3 septa in it
• All septa are break and form fragment
• These fragment developed in to new mitochondria

2- From E.R. or Plasma Membrane Morison

• According to this theory – Plasma membrane and E.R. formed many fold in it,
• These fold make a cylindrical structure.
• These cylindrical structure are curved and form new mitochondria

3- Prokaryotic origin

Altman & sagar

• According to this theory – Mitochondria are self biogenic unit
• Mitochondria and bacteria have many similarity so there origin is accepted form prokaryotic structure.
• Many years ago these prokaryotic cell enter in to the Eukaryotic cell and live as symbiosis. Which are today is known as mitochondria.